Social anxiety has a significant negative impact on the individual’s everyday life through handicapping process of social adaptation. In this regard, psychologists observe an increasing amount of research focused on coping-strategies in social phobia. Humorous reactions on stressful events are considered an important and effective coping strategy. The objective of this research is to study the impact of the humour as a coping strategy on different manifestations of social anxiety, as well as the associated feelings of guilt and shame in healthy people and patients with schizophrenia. The study involved 34 patients with schizophrenia and 102 healthy people, aged 18 to 35, males and females. As a research method we used questionnaires such as Liebowitz Social Anxiety Scale, Fear of Negative Evaluation Scale, Guilt and Shame Proneness Scale. The results showed that patients with schizophrenia are less likely to use humour as a coping strategy than healthy people. The results of one-way ANOVA method demonstrated that humour as a coping strategy is effective in some, but not all, aspects of social anxiety. The results of two-way ANOVA method showed that humour as a coping strategy could be effective to cope with shame and guilt, but at low level of social anxiety. At high level of social anxiety humour could not only be ineffective to cope with shame and guilt, but also have a negative influence on these emotions. In healthy males with low level of social anxiety humour helps to cope with withdrawal actions in shame. In males with schizophrenia and low levels of social anxiety humour reduces repair actions in guilt. These results indicate heterogenic influence of humour over social anxiety, shame and guilt, and can be used for diagnostic purposes and for psychocorrection.