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Effect of cross-sex hormones on the quality of life in transgenders

Effect of cross-sex hormones on the quality of life in transgenders

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Recieved: 09/12/2022

Accepted: 09/20/2022

Published: 03/16/2023

Keywords: transgenderism; transsexuals; sex correction; subjective quality of life; gender identity

p.: 44-54

DOI: 10.11621/npj.2023.0104

Available online: 16.03.2023

To cite this article:

Kumchenko, S.K., Tkhostov, A.Sh., Rasskazova, E.I. . Effect of cross-sex hormones on the quality of life in transgenders. // National Psychological Journal 2023. 1. p.44-54. doi: 10.11621/npj.2023.0104

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Issue 1, 2023

Kumchenko, S.K. Lomonosov Moscow State University

Tkhostov, A.Sh. Lomonosov Moscow State University

Rasskazova, E.I. Lomonosov Moscow State University

Abstract

Background. There is an increase in demand for transgender transition, which is connected with social causes, as well as the possibilities of modern medicine. One of the stages includes hormone replacement therapy (HRT). There is no clear opinion on the effect of HRT on subjective well-being of transsexuals. A controversial point is the ambiguous effect of HRT. 

Objective. To compare the effect of HRT on the subjective quality of life of transgender and compare the results with other stages of transgender transition, as well as with a control group with cisgender people. 

Methods. The anonymous questionnaire includes the life satisfaction scale (Osin, Leontiev, 2008), and the Kuhn test “Who am I?” modified by A. Tkhostov, E. Rasskazova, V. Emelin (2014). ANOVA is used in the SPSS 23 program. 

Sample. Control group included 120 cisgender people. Research group consisted of 151 transsexuals. The main group is divided by gender (MtF — Male-to-Female; FtM — Female-to-Male) and the stage of transgender transition. 

Results. All transsexuals at the HRT stage demonstrate a low significance of self-identification in the “Who am I?” test (P < 0.001), which is not observed at other stages of gender correction. HRT has diametrically different effects on MtF and FtM. MtFs demonstrate low subjective quality of life (P < 0.001) and low social recognition scores (P < 0.001), while FtM — on the contrary. 

Conclusion. The stage of hormone replacement therapy in transsexuals is associated with a revision of identity, in which old self-identities lose relevance, and new ones have not yet been found. Perhaps the uncertain and crisis nature of such a psychological situation is the reason for the ambiguous effect of hormone therapy on the subjective quality of life of transsexuals in many scientific publications.


References

Agarkov, S.T., Kashchenko, E.A. (2015). Sexuality from conception to death: the ontogeny of sexuality. M.: Izdatel’skie resheniya. (In Russ.). 

Baker, K., Wilson, L., Sharma, R., Dukhanin, V., McArthur, K., Robinson, K. (2021). Hormone Therapy, Mental Health, and Quality of Life Among Transgender People: A Systematic Review. Journal of the Endocrine Society, 5 (4), bvab011. 

Coleman, E., Bockting, W., Botzer, M., Cohen-Kettenis, P. (2012). Standards of Care for the Health of Transsexual, Transgender, and Gender-Nonconforming People, Version 7. International Journal of Transgenderism, 1, 13 (4), 165–232. 

Colizzi, M., Costa, R., Todarello, O. (2014). Transsexual patients’ psychiatric comorbidity and positive effect of cross-sex hormonal treatment on mental health: results from a longitudinal study. Psychoneuroendocrinology, 39, 65–73. 

Costa, R., Colizzi, M. (2016). The effect of cross-sex hormonal treatment on gender dysphoria individuals’ mental health: A systematic review. Neuropsychiatric Disease and Treatment, 12, 1953–1966. 

Gómez-Gil, E., Zubiaurre-Elorza, L., Esteva, I., Guillamon, A. et al. (2012). Hormone-treated transsexuals report less social distress, anxiety and depression. Psychoneuroendocrinology, 37 (5), 662–670. 

Goodfriend, W., Garcia, A., Hoover, A., Habashi, M., Hack, T., Raymond, A. (2022). Identity Development and Self-Esteem in Transgender Men: The Importance of Masculinity. Journal of Homosexuality, 22, 1–21. 

Harper, J., O’Donnell, E., Sorouri Khorashad, B., McDermott, H., Witcomb, G. (2021). How does hormone transition in transgender women change body composition, muscle strength and haemoglobin? Systematic review with a focus on the implications for sport participation. British Journal of sports medicine, 55 (15), 865–872. 

Karagapolov, V. (2016). Psychotherapeutic support for transgender people. In I. Karagapolova, N. Yur’eva, D. Ivanova (Eds.), Gender Journey: Collection of Papers. Issue 1. Diversity of identities. Variety of sexuality. Intersex Variations (pp. 69–80). M.: Masterskaya “Illyuminator”. (In Russ.). 

Karagapolova, I.V. (2017), Transgender in modern psychology of sexuality. In E. Kashchenko (Eds.), Essays on the Modern Psychology of Sexuality. M.: Ridero. (In Russ.). 

Kirej-Sitnikova, YA. (2021). Social factors in the design of epidemiological studies of the effectiveness of medical procedures for transgender transition (analytical review). Social’nye aspekty zdorov’ya naseleniya (Social aspects of public health), 67 (6), 8. (Retrieved from http://vestnik.mednet.ru/content/view/1322/30/lang,ru/) (review date: 05.09.2022). (In Russ.). 

Klemmer, C., Arayasirikul, S., Raymond, H. (2021). Transphobia-Based Violence, Depression, and Anxiety in Transgender Women: The Role of Body Satisfaction. Journal of interpersonal violence, 36 (5–6), 2633–2655. 

Kumchenko, S.K., Demedeckaya, Ya.A. (2018). Specific ratio of transsexuals in Russian-speaking countries. Psihologiya. Istoriko-kriticheskie obzory i sovremennye issledovaniya (Psychology. Historical-critical Reviews and Contemporary Research), 7 (1A), 145–155. (In Russ.). 

Kumchenko, S., Rasskazova, E., Tkhostov, A., Emelin, V. (2020). Preference for masculine or feminine gender roles and its relationship to well-being in transgender persons: Comparing pre-treatment, hormonal therapy, and post-surgery groups. Behavioral Sciences, 10 (6), 100–108. 

Lampinen, J.M., Odegard, T.N., Leding, J.K. (2003). Diachronic Disunity. Diachronic disunity. In D.R. Beike, J.M. Lampinen, & D.A. Behrend (Eds.), The Self and memory (pp. 227–253). NY: Psychology Press. 

Nguyen, H., Chavez, A., Lipner, E., Hantsoo, L., Kornfield, S., Davies, R., Epperson, C. (2018). Gender-Affirming Hormone Use in Transgender Individuals: Impact on Behavioral Health and Cognition. Current Psychiatry Reports, 20 (12), 110. 

Nobili, A., Glazebrook, C., Arcelus, J. (2018). Quality of life of treatment-seeking transgender adults: A systematic review and meta-analysis. Reviews in Endocrine and Metabolic Disorders, 19 (3), 199–220. 

Osin, E.N., Leont’ev, D.A. (2008). Approbation of Russian-language versions of two scales for rapid assessment of subjective well-being. Materials of the III All-Russian Sociological Congress. M.: In-t sociologii RAN; Rossijskoe obshchestvo sociologov. (In Russ.). 

Owen-Smith, A., Gerth, J., Sineath, R., Barzilay, J. et al. (2018). Association Between Gender Confirmation Treatments and Perceived Gender Congruence, Body Image Satisfaction, and Mental Health in a Cohort of Transgender Individuals. The Journal of Sexual Medicine, 15 (4), 591–600. 

Papadopulos, N., Ehrenberger, B., Zavlin, D., Lellé, J. et al. (2021). Quality of Life and Satisfaction in Transgender Men After Phalloplasty in a Retrospective Study. Annals of Plastic Surgery, 87, 91–97. 

Papadopulos, N., Lellé, J., Zavlin, D., Herschbach, P. et al. (2017). Quality of Life and Patient Satisfaction Following Male-to-Female Sex Reassignment Surgery. The Journal of Sexual Medicine, 14 (5), 721–730. 

Passos, T., Teixeira, M., Almeida-Santos, M. (2020). Quality of Life After Gender Affirmation Surgery: A Systematic Review and Network Meta-analysis. Sexuality Research and Social Policy, 17 (2), 252–262. 

Petrova, N.N., Chumakov, E.M., Limankin, O.V., Azarova, L.A. (2021 Issues of gender identity and provision of psychiatric care. Social’naya i klinicheskaya psihiatriya (Social and Clinical Psychiatry), 31 (1), 80–89. (In Russ.). 

Rowniak, S., Bolt, L., Sharifi, C. (2019). Effect of cross-sex hormones on the quality of life, depression and anxiety of transgender individuals: A quantitative systematic review. Joanna Briggs Institute Database of Systematic Reviews & Implementation Report, 17 (9), 1826–1854. 

Simbar, M., Nazarpour, S., Mirzababaie, M., Emam Hadi, M., Ramezani Tehrani, F., Alavi Majd, H. (2018). Quality of Life and Body Image of Individuals with Gender Dysphoria. Journal of Sex & Marital Therapy, 44 (6), 523–532. 

Tkachenko, A.A. (2003). An abnormal sexual behavior. SPb.: Yuridicheskij centr Press. (In Russ.). 

Tkhostov, A.Sh. (2020). Cultural-historical pathopsychology. M.: Kanon+. (In Russ.). 

Tkhostov, A.Sh., Rasskazova, E.I. (2012). Identity as a psychological construct: the possibilities and limitations of an interdisciplinary approach. Psihologicheskie issledovaniya (Psychological Research), 5 (26). (Retrieved from https://psystudy.ru/index.php/num/article/view/741) (review date: 05.09.2022). (In Russ.). 

Tkhostov, A.Sh., Rasskazova, E.I., Emelin, V.A. (2014). Psychodiagnostics of the subjective perception of one’s identifications: the use of the modified methodology “Who am I?” Natsional’nyy psihologicheskiy zhurnal (National psychological journal), 2 (14), 58–69. (In Russ.). 

Vygotsky, L.S. (1984). Collected Works (4th ed.). M.: Pedagogika. (In Russ.). 

Wernick, J., Busa, S., Matouk, K., Nicholson, J., Janssen, A. (2019). A Systematic Review of the Psychological Benefits of Gender-Affirming Surgery. Urologic Clinics of North America, 46 (4), 475–486. 

Wiik, A., Lundberg, T., Rullman, E., Andersson, D. et al. (2020). Muscle Strength, Size, and Composition Following 12 Months of Gender-affirming Treatment in Transgender Individuals. The Journal of clinical endocrinology and metabolism, 1, 105 (3), 247. 

White Hughto, J., Reisner, S. (2016). A Systematic Review of the Effects of Hormone Therapy on Psychological Functioning and Quality of Life in Transgender Individuals. Transgender Health, 1 (1), 21–31. 

Yang, X., Wang, L., Hao, C., Gu, Y. et al. (2015). Sex Partnership and Self-Efficacy Influence Depression in Chinese Transgender Women: A Cross-Sectional Study. PLoS One, 10 (9), e0136975. 

Yang, X., Zhao, L., Wang, L., Hao, C. et al. (2016). Quality of Life of Transgender Women From China and Associated Factors: A Cross-Sectional Study. The Journal of Sexual Medicine, 13 (6), 977–987.


To cite this article:

Kumchenko, S.K., Tkhostov, A.Sh., Rasskazova, E.I. . Effect of cross-sex hormones on the quality of life in transgenders. // National Psychological Journal 2023. 1. p.44-54. doi: 10.11621/npj.2023.0104

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