Planning disorders in patients with schizophrenia: potential role of short-term memory and attention

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Recieved: 07/16/2021

Accepted: 07/29/2021

Published: 07/30/2020

Keywords: executive function; planning; schizophrenia; short-term memory; attention; abstract thinking

p.: 51-60

DOI: 10.11621/npj.2021.0205

Available online: 30.07.2021

To cite this article:

Alekseev Andrey A. , Rupchev George E. , Tkhostov, A.Sh.. Planning disorders in patients with schizophrenia: potential role of short-term memory and attention. // National Psychological Journal 2021. 2. p.51-60. doi: 10.11621/npj.2021.0205

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Alekseev Andrey A. Lomonosov Moscow State University

Rupchev George E. Lomonosov Moscow State University, The Mental Health Research Center

Tkhostov, A.Sh. Lomonosov Moscow State University

Abstract

Background. Although planning disorders in schizophrenia are a fairly reliably established fact, the mechanisms of these disorders remain not fully clarified. Given the complex nature of planning, the presence of its disturbances can be influenced by disturbances of other mental processes.

Objective. Comparison of the links between planning, short-term memory, attention and abstract thinking in patients with schizophrenia and in normal.

Design. 50 patients with schizophrenia (14 females, age 34.92 ± 8.54; illness duration 8.34 ± 5.87) and 50 healthy volunteers (14 females, age 32.42 ± 7.26) were examined. Assessment included: Tower of London-Test (TOL-DX) for planning assessment; Benton’s test (BVTR) for short-term memory assessment; sub-test Similarity (from WAIS) for abstract thinking assessment; Schulte Tables for assessment of attention; Wisconsin Card Sorting Test to assess cognitive flexibility.

Results. Patients showed significantly worse results in all parameters, which indicates that patients have impairments in all assessed cognitive functions. The revealed relationships between planning and other cognitive processes in schizophrenic patients and healthy subjects were significantly different. In healthy subjects, the effectiveness of planning was found to be associated only with abstract thinking. At the same time, in patients with schizophrenia, associations were found between the effectiveness of planning and all the other cognitive processes (short-term memory, attention, set-shifting).

Conclusion. The preservation of planning in schizophrenia is associated with the preservation of other mental processes. Short-term memory and attention are necessary, but not sufficient conditions for the realization of the planning process.

References

Alekseev A.A., Rupchev G.E., Katenko S.V. (2012). Impairments of planning in schizophrenia. Psikhologicheskie Issledovaniya (Psychological research), 5 (23), 9. Retrieved from: http://psystudy.ru/index.php/num/2012v5n23/679-alekseev23.html (review date: 24.05.2021). (in Russ.).

Karyakina M.V., Shmukler A.B. (2020). Neurocognitive impairments in patients with schizophrenia and schizophrenia spectrum disorders: cluster analysis results. Obozrenie psihiatrii i medicinskoj psihologii imeni V.M. Bekhtereva (Review of Psychiatry and Medical Psychology named after V.M. Bekhterev), 1, 45–51. (in Russ.). doi:10.31363/2313-7053-2020-1-45-51

Rubinstein S.Ya. (2010). Experimental methods of pathopsychology. Moscow: Izd-vo instituta Psihoterapii. (in Russ.).

Filimonenko Y., Timofeev V. (1993). Guide to the method of research of intelligence in adults D. Veksler (WAIS). Saint-Petersburg: GP “Imaton”. (in Russ.).

Aubin G., Stip E., Gélinas I., Rainville C., Chapparo C. (2009). Daily activities, cognition and community functioning in persons with schizophrenia. Schizophrenia Research, 107 (2–3), 313–318. doi:10.1016/j.schres.2008.08.002

Ayesa-Arriola R., Setién-Suero E., Neergaard K.D., Belzunces A.A., Contreras F., van Haren N.E.M., Crespo-Facorro B. (2018). Premorbid IQ subgroups in first episode non affective psychosis patients: Long-term sex differences in function and neurocognition. Schizophrenia Research, 197, 370–377. doi:10.1016/j.schres.2017.12.006

Baliga S.P., Kamath R.M., Kedare J.S. (2020). Subjective cognitive complaints and its relation to objective cognitive performance, clinical profile, clinical insight, and social functioning in patients of schizophrenia: A cross-sectional study. Indian Journal of Psychiatry, 62 (2), 178–185. doi:10.4103/psychiatry.IndianJPsychiatry_639_19

Berberian A.A., Gadelha A., Dias N.M., Mecca T.P., Comfort W.E., Bressan R.A., Lacerda A.T. (2019). Component mechanisms of executive function in schizophrenia and their contribution to functional outcomes. Brazilian journal of psychiatry, 41 (1), 22–30. doi:10.1590/1516-4446-2018-0021

Brown K.D., Schmitter-Edgecombe M. (2020). Effects of initial planning on task execution performance of older adults: A naturalistic assessment paradigm. Journal of clinical and experimental neuropsychology, 42 (1), 1–13. doi:10.1080/13803395.2019.1680610

Carruthers S.P., Gurvich C.T., Meyer D., Bousman C., Everall I.P., Neill E., Pantelis C., Sumner P.J., Tan E.J., Thomas E.H.X., Van Rheenen T.E., Rossell S.L. (2019). Exploring Heterogeneity on the Wisconsin Card Sorting Test in Schizophrenia Spectrum Disorders: A Cluster Analytical Investigation. Journal of the International Neuropsychological Society: JINS, 25 (7), 750–760. doi:10.1017/S1355617719000420

Chang W.C., Liu J.T.T., Hui C.L.M., Chan S.K.W., Lee E.H.M., Suen Y.N., Chen E.Y.H. (2019). Executive dysfunctions differentially predict amotivation in first-episode schizophrenia-spectrum disorder: a prospective 1-year follow-up study. European archives of psychiatry and clinical neuroscience, 269 (8), 887–896. doi:10.1007/s00406-018-0918-y

Chen C.K., Lee C.Y., Lee Y., Hung C.F., Huang Y.C., Lee S.Y., Huang M.C., Chong M.Y., Chen Y.C., Wang L.J. (2018). Could schizoaffective disorder, schizophrenia and bipolar I disorder be distinguishable using cognitive profiles? Psychiatry Research, 266, 79–84. doi:10.1016/j.psychres.2018.05.062

Culbertson W.C., Zillmer E.A. (1999). The Tower of London, Drexel University, research version: Examiner’s manual. N.Y.: Multi-Health Systems.

Dorofeikova M., Neznanov N., Petrova N. (2018). Cognitive deficit in patients with paranoid schizophrenia: Its clinical and laboratory correlates. Psychiatry Research, 262, 542–548. doi:10.1016/j.psychres.2017.09.041

Fernández-Sevillano J., González-Pinto A., Rodríguez-Revuelta J., Alberich S., Gónzalez-Blanco L., Zorrilla I., Velasco A., López M.P., Abad I., Sáiz P.A. (2021). Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits. Journal of Affective Disorders, 1 (278), 488–496. doi:10.1016/j.jad.2020.09.044

Friedman N.P., Miyake A. (2017). Unity and diversity of executive functions: Individual differences as a window on cognitive structure. Cortex, 86, 186–204. doi:10.1016/j.cortex.2016.04.023

Gold J.M., Robinson B., Leonard C.J., Hahn B., Chen S., McMahon R.P., Luck S.J. (2018). Selective Attention, Working Memory, and Executive Function as Potential Independent Sources of Cognitive Dysfunction in Schizophrenia. Schizophrenia Bulletin, 17, 44 (6), 1227–1234. doi:10.1093/schbul/sbx155

Heaton R.K., Chelune G.J., Talley J.L., Kay G., Curtiss G. (1993). Wisconsin Card Sorting Test manual: Revised and expanded. Odessa, FL: Psychological Assessment Resources.

Kaneko K. (2018). Negative Symptoms and Cognitive Impairments in Schizophrenia: Two Key Symptoms Negatively Influencing Social Functioning. Yonago acta medica, 18, 61 (2), 91–102. doi:10.33160/yam.2018.06.001

Khalil A.H., El-Meguid M.A., Bastawy M., Rabei S., Ali R., Elmoneam M.H.E.A. (2020). Correlating cognitive functions to symptom domains and insight in Egyptian patients with schizophrenia. The International journal of social psychiatry, 66 (3), 240–248. doi:10.1177/0020764019897697

Knapp F., Viechtbauer W., Leonhart R., Nitschke K., Kaller C.P. (2017). Planning performance in schizophrenia patients: a meta- analysis of the influence of task difficulty and clinical and sociodemographic variables. Psychological medicine, 47 (11), 2002– 2016. doi:10.1017/S0033291717000459

Lexén A., Hofgren C., Stenmark R., Bejerholm U. (2016). Cognitive functioning and employment among people with schizophrenia in vocational rehabilitation. Work, 54 (3), 735–44. doi:10.3233/WOR-162318

Mihaljević-Peleš A., Bajs Janović M., Šagud M., Živković M., Janović Š., Jevtović S. (2019). Cognitive deficit in schizophrenia: an overview. Psychiatria Danubina, 31 (Suppl 2), 139–142.

Palsetia D., Chandrasekhar K., Reddy M.S., De Sousa A., Karia S. (2018). Executive function in patients with schizophrenia based on socio-occupational impairment: A cross-sectional study. Industrial psychiatry journal, 27 (2), 181–189. doi:10.4103/ipj.ipj_85_18

Shallice Т. (1982). Specific impairments of planning. Philosophical Transactions of the Royal Society of London, 298, 199–209.

Sheffield J.M., Karcher N.R., Barch D.M. (2018). Cognitive Deficits in Psychotic Disorders: A Lifespan Perspective. Neuropsychology review, 28 (4), 509–533. doi:10.1007/s11065-018-9388-2

Siddiqui I., Saperia S., Fervaha G., Da Silva S., Jeffay E., Zakzanis K.K., Agid O., Remington G., Foussias G. (2019). Goal-directed planning and action impairments in schizophrenia evaluated in a virtual environment. Schizophrenia Research, 206, 400–406. doi:10.1016/j.schres.2018.10.012

Sivan A.B. (1992). Benton Visual Retention Test: Fifth Edition. San Antonio, TX: Psychological Corporation.

Thai M.L., Andreassen A.K., Bliksted V. (2019). A meta-analysis of executive dysfunction in patients with schizophrenia: Different degree of impairment in the ecological subdomains of the Behavioural Assessment of the Dysexecutive Syndrome. Psychiatry Research, 272, 230–236. doi:10.1016/j.psychres.2018.12.088

Tiryaki A., Karahan A., Arslan F.C. (2018). The Relationship of Insight with Psychopathology and Neuropsychological Functioning in Patients with Schizophrenia. Turkish journal of psychiatry, 29 (1), 22–30.

Watson A.J., Joyce E.M., Fugard A.J.B., Leeson V.C., Barnes T.R.E., Huddy V. (2017). More haste less speed: A meta-analysis of thinking latencies during planning in people with psychosis. Psychiatry Research, 258, 576–582. doi:10.1016/j.psychres.2017.09.003

Zanelli J., Mollon J., Sandin S. (2019). Cognitive change in schizophrenia and other psychoses in the decade following the first episode. American Journal of Psychiatry, 176 (10), 811–819. doi:10.1176/appi.ajp.2019.18091088

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